Molecular models

Molecular models are an indispensable tool in chemistry for teaching as well as for more sterically complex scientific discussions.

3D-printed molecular models go beyond the aspects of generalized geometry, which is mapped with the help of typical molecular construction kits. These represent an exact true-to-scale representation of reality. The atomic coordinates are taken either from X-ray crystallographic structure determinations or from quantum chemical calculations.

After scaling, typically by a factor of 1 : 1.^8-108, and converting the coordinate files into 3-dimensional shapes, the structures, which are then approx. 20 cm in size, are 3D printed. The exact geometric ratios can be measured or examined using a ruler or triangle.

This opens up innovative teaching methods in advanced lectures/exercises in organic chemistry (stereochemistry), e.g. with regard to determining the double bond character, aromaticity and numerous other properties. In addition, the models allow a clear discussion of complex research problems.

Chem. Teach. Int. 2020, 2, 20190006: Organic chemistry lecture course and exercises based on true scale models